Cosmetic dermatologists want to understand the physiology of skin—notably skin conditions they consider problematic and in need of treatment—whereas product developers would like to create a cosmetic product that treats this problematic skin in order to change its appearance. They are therefore all starting with the same problem in order to get effective, though respectively different, treatments.
A Dermatological View: From Physiology to Therapy is designed to satisfy both sides of the problematic skin equation. Written in partnership with numerous colleagues, Dr. Howard I. Maibach’s aim is ever toward medical advancement and sustained product development in his areas of primary clinical specialty and research-based interest, including dermatopharmacology, allergic contact dermatitis, and dermatotoxicology and pathology. The information in A Dermatological View is purposed to both illuminate and to instruct. Topics include:
Ethnic variation in skin properties
Physiological and methodological aspects of normal and damaged skin types
Enhanced skin penetration, including occlusive effects and active delivery systems
Skin sensitivity and allergic contact dermatitis
Anti-aging, -itch and –inflammation
And more!
Table of Contents
Introduction by Johann W. Wiechers, PhD
Foreword
Section One: Normal Skin—Physiological and Methodological Aspects
1: Ethnic Variation in Skin Properties: Quo Vadis? Part I
2: Ethnic Variation in Skin Properties: Quo Vadis? Part II
3: Variations in Pigmentation and Ultrastructural Skin Differences Among Ethnic Groups
4: Advances in Stratum Corneum Biology and Understanding of Dry Skin
5: Bioengineering Analysis of Water Hydration
6: Skin Friction Coefficient Values
7: Ceramides in Healthy and Diseased Skin
8: Hormesis and Cosmetic Dermatology
9: Tandem Irritants with Synergistic, Additive or Quenching Effects on the Skin
Section Two: Damaged Skin—Physiological and Methodological Aspect
— 2.1 Mechanical Damage
10: Ceramides in Skin Stress: Ultraviolet, Tape Stripping and Crowding
11: Effects of Occlusion: Wound Healing
12: Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics
13: Cosmetic Utilization of Micro Wound Healing Models
— 2.2 Chemical Damage
2.2.1 Enhanced Skin Penetration
14: Squanometry: An Early Predictor of Changes in the Skin Barrier
15: Effects of Occlusion: Percutaneous Absorption
16: In vitro Model for Decontamination of Human Skin
17: Mechanisms of Tape Stripping and Protein Quantification
18: Tape Stripping Method in Humans: Comparison of Evaporimetric Methods
19: Correlating Transepidermal Water Loss and Percutaneous Absorption: An Overview
20: Predicting the Percutaneous Penetration of Cosmetic Ingredients
21: Clinical Relevance of Topical Active Delivery Systems in Cosmetics
2.2.2 Sensitive Skin
22: Three Decades of Patch Testing: Trends in a North American Populace
23: Sensitive Skin Syndrome: Sensory Response and Classification
24: Sensitive Skin Syndrome: Methodological Approaches
25: Sensitive Skin Syndrome: Relationships Among Factors
2.2.3 Allergic and Irritant Contact Dermatitis
26: Gender and Dermatitis
27: The Hardening Phenomenon in Irritant Contact Dermatitis: Cosmetic Implications
28: Effects of Occlusion: Irritant and Allergic Contact Dermatitis
29: Evaluating ACD Frequency After Reducing Exposure to Sensitizers
30: Defining Clinically Relevant Fragrance Allergens: The Challenge (Part I)
31: Defining Clinically Relevant Fragrance Allergens: The Challenge (Part II)
32: Allergic Contact Dermatitis to Linalool
— 2.3 UV-damaged Skin
33: Cutaneous Blood Flow in Aging Skin
34: Cutaneous Biochemistry in Aging Skin
35: Thickness of Aging Skin
Section Three: Cosmetic Therapies for Troubled Skin
— 3.1 Acnetic Skin
36: Keratolytic Treatments for Acne: A Review
— 3.2 Anti-aging, -itch, inflammation, and Antioxidants
37: Therapeutic Peptides in Aged Skin
38: Evaluating Antipruritics
39: Effect of Seawater Salts on Inflammatory Skin Disease
40: Chemoprevention of Skin Cancer: Role of Antioxidants
41: Antioxidant Inhibits UV Erythema In vivo in Humans
42: Using Photochemiluminescence to Quantify the Antioxidative Capacity of Topicals
43: A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity
— 3.3 Skin Moisturizers
44: Advances in Dry Stratum Corneum Biology and Moisturization
45: Moisturizer Efficacy: Evidence on Preventing and Treating Irritant Dermatitis
— 3.4 UV Protection
46: Enhancing Sunscreen Efficacy for Realistic Application
— 3.5 Woundhealing
47: Occlusion as an Active Agent
— 3.6 Translating Skin Physiology into Cosmetic Products
48: Personal Care Products for Men
Index
